3800 Reading Road is reported to have been designed by architect Matthew Burton for William O'Dell and completed in 1919. Burton's family was actually involved in the development of Avondale and in fact there is a street named 'Burton' for the family there. The Burton's were also related to the Mitchells (according to W. Langsam). Yes, 'Mitchell' of Mitchell Avenue fame. Members of the Mitchell family lived in Avondale and both the Rose Hill neighborhood and the Dakota neighborhoods in Avondale were deleveloped by them. Burton also designed the wonderful Frank Enger House at Dakota and Marion Avenues in Avondale (Langsam).
3800 Reading Road was eventually used as The Jewish Center for a time, beginning in 1935.